Is advanced paternal age a health risk for the offspring?
نویسندگان
چکیده
منابع مشابه
Advanced paternal age increases risk of bipolar disorder in offspring.
ED FROM Frans EM, Sandin S, Reichenberg A, et al. Advancing paternal age and bipolar disorder. Arch Gen Psychiatry 2008;65:1034–40. Correspondence to: Emma M Frans, MMedSc, Department of Medical Epidemiology and Biostatistics, Karolinksa Institute, PO Box 281, SE-171 77 Stockholm, Sweden; [email protected] Source of funding: None reported. c A table is published online only at http://ebmh.bmj.co...
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BACKGROUND Since 1958 many, but not all studies have demonstrated that paternal age is a risk factor for schizophrenia. There may be many different explanations for differences between studies, including study design, sample size, collection criteria, heterogeneity and the confounding effects of environmental factors that can for example perturb epigenetic programming and lead to an increase in...
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OBJECTIVE Advanced paternal age (APA) at conception has been linked with autism and schizophrenia in offspring, neurodevelopmental disorders that affect social functioning. The current study explored the effects of paternal age on social development in the general population. METHOD We used multilevel growth modeling to investigate APA effects on socioemotional development from early childhoo...
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OBJECTIVE To investigate whether advanced paternal age is associated with increased psychotic-like experiences (PLEs) and increased sensitivity to Cannabis in the offspring. METHODS A cross-sectional population-based study in 1684 participants aged 18 to 25. RESULTS We found no association of paternal age with PLEs. Only the positive dimension subscale was associated to paternal age, but th...
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a r t i c l e i n f o In view of disease risk, Kong et al. (2012) demonstrated that most of the new mutations are explained by the age of the father at conception. Accordingly, paternal age effects have been found for a variety of offspring traits, from physical and mental health to intelligence. Here, we investigated whether facial attractiveness is significantly associated with paternal age. ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2017
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2016.12.019